Know when not to recommend Otrivine Extra Dual Relief
KNOW WHEN NOT TO
RECOMMEND OTRIVINE EXTRA DUAL RELIEF
CONTRAINDICATIONS
Otrivine Extra Dual Relief should not be given to:
- Those under 18 years of age, due to lack of sufficient evidence
- Customers with known hypersensitivity to the active substances or to any other ingredients in the product
- Customers with known hypersensitivity to atropine or similar substances (e.g. hyoscyamine and scopolamine)
- Customers who have had pituitary or brain surgery carried out through the nose or where dura mater may have been penetrated during surgery
- Customers with glaucoma (increased pressure in the eye)
- Customers with rhinitis sicca (characterised by an extremely dry nose)
PREGNANCY AND BREAST FEEDING
Otrivine Extra Dual Relief should not be recommended in pregnancy.
Advise pregnant women to consult their doctor about the use of the product in pregnancy.
Advise women who are breastfeeding to consult their doctor before using the product. The mother's need for treatment with Otrivine Extra Dual Relief and the advantages of breast feeding must be weighed against the potential risks to the infant.
CHECK FOR DRUG INTERACTIONS9
It's important to check that the customer is not taking any other product containing ipratropium bromide, or any other anticholinergic drugs, including the antihistamines chlorphenamine and diphenhydramine.
Check customers are not taking:
- Monoamine oxidase inhibitors (MAOIs) e.g. phenelzine, selegiline,
- Tri- or tetra-cyclic antidepressants e.g amitriptyline.
Concomitant use or use within the last 2 weeks of tri-cyclic antidepressants and sympathomimetic preparations may result in an increased sympathomimetic effect of xylometazoline (resulting in raised blood pressure and inducing vasoconstriction) and is therefore not recommended.
Concomitant use or use within the last 2 weeks of sympathomimetic preparations (preparations which act as agonists of the sympathetic nervous system; effects include stimulating the heart and inducing vasoconstriction, e.g phenylephrine) may induce severely elevated blood pressure and is therefore not recommended. In critical cases of elevated blood pressure, treatment with Otrivine Extra Dual Relief should be discontinued and the elevated blood pressure treated.
CAUTIONS
Caution should be exercised when recommending to customers with:
- Hypertension, cardiovascular diseases
- Hyperthyroidism, diabetes mellitus
- Hypertrophy of the prostate, stenosis of the bladder bar
- Pheochromocytoma (a type of adrenal gland tumour)
- Sensitivity to adrenergic substances such as adrenaline or noradrenaline - may give symptoms such as sleeping disturbances, dizziness, tremor, cardiac arrhythmias or elevated blood pressure
And customers predisposed to:
- Angle closure glaucoma
- Epistaxis (nosebleeds)
- Paralytic ileus (a form of intestinal blockage)
- Cystic fibrosis
Be alert and always refer customers with any of the following symptoms to their doctor:
- Persistent productive cough
- Chest pain
- Shortness of breath