Stays effective up to 36 hours and starts working from 30 minutes after administration. With less time pressure, intimacy can feel more natural11
Requires a local release of nitric oxide to produce an erection, meaning it only works alongside sexual stimulation. Reversible inhibition of cGMP-specific PDE5, so an erection should subside after sexual activity
Increases spontaneity and reduces time concerns significantly more than sildenafil 50mg11,16
Tadalafil is supported by 20 years of real-world clinical experience as a prescription-only medicine,27 so patients can feel confident in a treatment that’s been used by 84 million men worldwide27
Absorption not affected by food, so patients have the flexibility to take it with or without food
Comparison with other OTC PDE5 inhibitors
Patients may ask what the differences are between OTC tadalafil 10mg and sildenafil 50mg. They are both PDE5 inhibitors and both are equally effective at improving erectile function,15 but one may suit your ED patient better.