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Resources and references

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Resources

The resources below will help you when recommending Maloff Protect. You can click on each heading to be taken directly to the resource as a downloadable pdf

maloff@glenmarkpharma.com

Open references
  1. World Health Organisation. World Malaria Report 2017. Accessed at http://www.who.int/malaria/publications/worldmalaria-report-2017/en/ (April 2018)
  2. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/660051/Guidelines_for_malaria_prevention_in_travellers_from_the_UK_2017.pdf
  3. https://www.gov.uk/government/publications/importedmalaria-in-the-uk-statistics
  4. https://www.gov.uk/government/publications/malariaprevention-transmission-symptoms/malaria-transmission-incubation-period-symptoms
  5. https://travelhealthpro.org.uk/factsheet/52/malaria
  6. https://www.nhs.uk/conditions/malaria/symptoms
  7. Data on file for research conducted by Hamell (2016) on behalf on Glenmark
  8. https://www.medicines.org.uk/emc/product/660
  9. https://www.medicines.org.uk/emc/product/947/smpc
  10. https://www.medicines.org.uk/emc/product/5490/smpc
  11. https://www.medicines.org.uk/emc/product/5494/smpc
  12. https://www.medicines.org.uk/emc/product/6262
  13. https://www.medicines.org.uk/emc/product/1108
  14. https://www.medicines.org.uk/emc/product/5493/smpc
  15. https://travelhealthpro.org.uk/country/192/senegal#Malaria
Product Information

Presentation: atovaquone 250mg, proguanil 100mg. Indication(s): Chemoprophylaxis of Plasmodium falciparum (P. falciparum) malaria in adults. Check official guidelines (e.g. World Health Organisation (WHO) and public health authorities' guidelines) before dispensing. Dosage: One tablet daily with food or a milky drink at the same time each day. Commence 1-2 days prior to entering malaria-endemic area, continue for the duration of the stay plus seven days after leaving the area. The maximum duration of travel for which Maloff Protect can be supplied without prescription is 12 weeks (93 tablets). For longer durations of travel, advice should be sought from a doctor or other qualified prescriber. Contraindications, precautions, side effects: Contraindications: hypersensitivity to atovaquone, proguanil or excipients, renal disease, hepatic impairment, children and adolescents. Precautions: if vomiting occurs within one hour of dosing repeat dose. If allergic reaction develops, discontinue use promptly and seek medical treatment. Refer the following patients to a doctor or other qualified prescriber: those taking etoposide, rifampicin, rifabutin, metoclopramide, warfarin and other anticoagulants, tetracycline, indinavir, efavirenz, zidovudine, boosted protease inhibitors, those with a history of depression or seizures, those with TB, patients who are pregnant, planning to become pregnant or those breast feeding. Safety and effectiveness has not been established in patients <40kg. Remind travellers of the need for a full travel consultation. The most common side effects are headache, abdominal pain and diarrhoea. Other important reactions reported are severe allergic reactions, pancytopenia in patients with severe renal impairment, severe skin reactions, seizure, hallucinations, liver inflammation, depression. Legal category: P. PL Holder: Glenmark Pharmaceuticals Europe Limited, Laxmi House, 2 B Draycott Avenue, Kenton, Middlesex, HA3 0BU. PL number: 25258/0166 RRP (excluding VAT): 24 Tablet Pack £39.00; 36 Tablet Pack £58.50 Date of preparation: 13 February 2018

Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk

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